available respondents and fitted to the study (because almost of the students suffered and aresuffering from acne). The needed data were completed and had been validated.The copies of the questionnaire were distributed personally by the researcher to therespondents. Just after a few minutes, all the copies distributed were retrieved also personally bythe researcher.
Facts and Myths about the Causes of AcneFactsMyths1.Stress1. Heredity with the exception of verysevere acne.2.Hormones (especially duringmenstruation)2. Food like pizza, chocolates, junk foods,greasy and fried foods.3.Oil-based make up, suntan oil andhair products.4.Cosmetics that are water based and oilfree skin care products.5.Hard Scrubbing of the Skin6.Pressure from helmets, chinstraps,collars and suspenders.7.Drugs because some medication canworsen acne.8.Occupations that is exposed toindustrial products like cutting oils.9.Squeezing or picking at blemishes.10.Environmental Irritants.
Table 1.1 Facts and myths about the causes of acne
The researchers conducted a survey on what age does acne occur on teenagers. Theresearchers have given this survey to 34 students in 4
year high school. And the results can beseen on table 1.2.
Acne is one of the most common dermatologic diseases, affecting between 40 and 50 million people each year. While best known as a bothersome part of puberty, affecting approximately 85% of teenagers, acne can persist or even first appear during adulthood, causing emotional and physical distress as well as permanent disfigurement.
A growing number of men and women in their 30s, 40s, 50s and even beyond are seeking treatment for acne. I think the point has been made: Acne is common, costing over $3 billion dollars per year in the US alone in treatment and loss of productivity.
So what’s new in our understanding of how we get acne and how to more effectively treat it?
Every year, studies are published highlighting the connection between diet and acne. What can we translate from this? Well it seems almost every aspect of the western diet, which contains high glycemic load, high fat and meat intake (with leucine), insulin- and IGF-1-level elevating dairy proteins -- which can increase oil production and skin cell growth resulting in blocked pores.
A recent study did find that participants who consumed omega fatty acids had less acne, and another study looking at a dietary supplement targeting acne did have a positive effect, though I think treating acne with diet alone is not going to emerge anytime soon as a solo therapy. I think what we can derive from this is that a well balanced, non-overindulgent diet is the way to go for more then just skin health.
Future directions in treatment
The enemy of my enemy is my friend: A recent paper found that a number of viruses called bacteriophages which live on the skin are very capable at killing the bacteria which is implicated in acne, P. acnes. How this will be translated to treatment is unclear but still very exciting.
Small is big: Nanotechnology for acne - Nanotechnology is the science of small…really small (1 billionth of a meter). Materials existing at this scale have unique properties and have a higher likelihood of reaching and interacting with their targets, here specifically P. acnes (the bacteria that causes acne) and the immune cells involved in creating those wonderfully painful and swollen acne lesions.
Researchers at University of California San Diego have developed a nano-based drug from lauric acid, which is found in coconut oil. Both in test tube and animal models of acne, they reported exciting results, so stay tuned. Along these lines, a trans-continental research team including yours truly developed a chitosan-based (derived from crab shells) nanoparticle which was able to kill P. acnes, prevent inflammation signals from infected cells, and could also be combined with benzoyl peroxide to be even more effective with fewer side effects then benzoyl peroxide alone.
Shine a light: Lasers for acne - Photodynamic therapy (PDT) is a treatment involving either a pulsed light source or a laser, in combination with a topical preparation known as Levulan. This therapy is approved for use in treating a precancerous skin condition associated with sun damage. The treatment kicks in when the light source activates properties in the Levulan that both destroy the bacteria and shrink the oil gland, returning production back to normal. Newer ways to improve the effects of Levulan include changes in the chemical structure of Levulan as well as nanotechnology for more effective and targeted delivery into the hair follicle.
Safety of Acne Treatments
There has been a great deal of negative publicity surrounding the use of isotretinoin (Accutane is one brand name), which is an oral medication derived from vitamin A that is the most effective treatment we have in the fight against severe acne. Fear-inducing side effects such as suicidal thoughts, inflammatory bowel disease, and hearing loss have been highlighted in the media inappropriately. All evidence to date refutes these proposed adverse effects.
While I do not recommend initiating this therapy on a whim, as it does require time, blood tests, and for women of child-bearing age, two forms of birth control, it should not be easily dismissed as it works really, really well. Standard treatment regimens based on a person’s body weight boast an 80% success rate. In a recent study, it was shown that by increasing this total dose, recurrence of acne in these patients was reduced from 20% to 12% without any increased risk of side effects. Paradigm shifts are not adopted overnight, but more research will hopefully support this finding to enable dermatologists to even more effectively treat their patients.
Every day, new research is furthering our understanding of acne, which will allow dermatologists to offer their patients better and safer treatments. Stay tuned for more!
Important: The views and opinions expressed in this article are those of the author and not Everyday Health. See More
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